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FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis
Fanconi anemia (FA) is a recessive X-linked and autosomal genetic disease associated with bone marrow failure and increased cancer, as well as severe germline defects such as hypogonadism and germ cell depletion. Although deficiencies in FA factors are commonly associated with germ cell defects, it...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550819/ https://ncbi.nlm.nih.gov/pubmed/26123487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv244 |
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