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FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis

Fanconi anemia (FA) is a recessive X-linked and autosomal genetic disease associated with bone marrow failure and increased cancer, as well as severe germline defects such as hypogonadism and germ cell depletion. Although deficiencies in FA factors are commonly associated with germ cell defects, it...

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Bibliografski detalji
Izdano u:Hum Mol Genet
Glavni autori: Kato, Yasuko, Alavattam, Kris G., Sin, Ho-Su, Meetei, Amom Ruhikanta, Pang, Qishen, Andreassen, Paul R., Namekawa, Satoshi H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550819/
https://ncbi.nlm.nih.gov/pubmed/26123487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv244
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