Visualizing Transient Watson-Crick Like Mispairs in DNA and RNA Duplexes

Rare tautomeric and anionic nucleobases are believed to play fundamental biological roles but their prevalence and functional importance has remained elusive because they exist transiently, in low-abundance, and involve subtle movements of protons that are difficult to visualize. Using NMR relaxatio...

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Bibliografische gegevens
Gepubliceerd in:Nature
Hoofdauteurs: Kimsey, Isaac J., Petzold, Katja, Sathyamoorthy, Bharathwaj, Stein, Zachary W., Al-Hashimi, Hashim M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547696/
https://ncbi.nlm.nih.gov/pubmed/25762137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14227
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