New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey

Hoogsteen (HG) base pairs (bps) provide an alternative pairing geometry to Watson–Crick (WC) bps and can play unique functional roles in duplex DNA. Here, we use structural features unique to HG bps (syn purine base, HG hydrogen bonds and constricted C1′–C1′ distance across the bp) to search for HG...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Zhou, Huiqing, Hintze, Bradley J., Kimsey, Isaac J., Sathyamoorthy, Bharathwaj, Yang, Shan, Richardson, Jane S., Al-Hashimi, Hashim M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Survey and Summary
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402545/
https://ncbi.nlm.nih.gov/pubmed/25813047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv241
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