New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey

Hoogsteen (HG) base pairs (bps) provide an alternative pairing geometry to Watson–Crick (WC) bps and can play unique functional roles in duplex DNA. Here, we use structural features unique to HG bps (syn purine base, HG hydrogen bonds and constricted C1′–C1′ distance across the bp) to search for HG...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhou, Huiqing, Hintze, Bradley J., Kimsey, Isaac J., Sathyamoorthy, Bharathwaj, Yang, Shan, Richardson, Jane S., Al-Hashimi, Hashim M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Survey and Summary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402545/
https://ncbi.nlm.nih.gov/pubmed/25813047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv241
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