New insights into Hoogsteen base pairs in DNA duplexes from a structure-based survey

Hoogsteen (HG) base pairs (bps) provide an alternative pairing geometry to Watson–Crick (WC) bps and can play unique functional roles in duplex DNA. Here, we use structural features unique to HG bps (syn purine base, HG hydrogen bonds and constricted C1′–C1′ distance across the bp) to search for HG...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Zhou, Huiqing, Hintze, Bradley J., Kimsey, Isaac J., Sathyamoorthy, Bharathwaj, Yang, Shan, Richardson, Jane S., Al-Hashimi, Hashim M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Survey and Summary
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402545/
https://ncbi.nlm.nih.gov/pubmed/25813047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv241
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