Loading...

A Historical Account of Hoogsteen Base-pairs in Duplex DNA

In 1957, a unique pattern of hydrogen bonding between N3 and O4 on uracil and N7 and N6 on adenine was proposed to explain how poly(rU) strands can associate with poly(rA)-poly(rU) duplexes to form triplexes. Two years later, Karst Hoogsteen visualized such a non-canonical A-T base-pair through X-ra...

Full description

Saved in:
Bibliographic Details
Main Authors: Nikolova, Evgenia N., Zhou, Huiqing, Gottardo, Federico L., Alvey, Heidi S., Kimsey, Isaac J., Al-Hashimi, Hashim M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844552/
https://ncbi.nlm.nih.gov/pubmed/23818176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22334
Tags: Add Tag
No Tags, Be the first to tag this record!