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Probing Transient Hoogsteen Hydrogen Bonds in Canonical Duplex DNA Using NMR Relaxation Dispersion and Single-atom Substitution

Nucleic acids transiently morph into alternative conformations that can be difficult to characterize at the atomic level by conventional methods because they exist for too little time and in too little abundance. We recently reported evidence for transient Hoogsteen base pairs in canonical B-DNA bas...

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書目詳細資料
Main Authors: Nikolova, Evgenia N., Gottardo, Federico L., Al-Hashimi, Hashim M.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791138/
https://ncbi.nlm.nih.gov/pubmed/22309937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2117816
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