Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling

The G protein-coupled receptor (GPCR) Smoothened (Smo) is the requisite signal transducer of the evolutionarily conserved Hedgehog (Hh) pathway. Although aspects of Smo signaling are conserved from Drosophila to vertebrates, significant differences have evolved. These include changes in its active s...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Marada, Suresh, Navarro, Gemma, Truong, Ashley, Stewart, Daniel P., Arensdorf, Angela M., Nachtergaele, Sigrid, Angelats, Edgar, Opferman, Joseph T., Rohatgi, Rajat, McCormick, Peter J., Ogden, Stacey K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546403/
https://ncbi.nlm.nih.gov/pubmed/26291458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005473
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