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Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation
Histone H2A monoubiquitylation (H2Aub) is considered to be a key effector in transcriptional repression by Polycomb-repressive complex 1 (PRC1). We analyzed Drosophila with a point mutation in the PRC1 subunit Sce that abolishes its H2A ubiquitylase activity or with point mutations in the H2A and H2...
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| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526733/ https://ncbi.nlm.nih.gov/pubmed/26178786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265439.115 |
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