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Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex

It is well established that Notch functions as a transcriptional activator through the formation of a ternary complex that comprises Notch, Maml and CSL. This ternary complex then serves to recruit additional transcriptional cofactors that link to higher order transcriptional complexes. The mechanis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Res
Prif Awduron: Han, Xiaoqing, Ranganathan, Prathibha, Tzimas, Christos, Weaver, Kelly L., Jin, Ke, Astudillo, Luisana, Zhou, Wen, Zhu, Xiaoxia, Li, Bin, Robbins, David J., Capobianco, Anthony J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581691/
https://ncbi.nlm.nih.gov/pubmed/28584023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0241
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