NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis

The Notch signaling pathway governs many distinct cellular processes by regulating transcriptional programs. The transcriptional response initiated by Notch is highly cell context dependent, indicating that multiple factors influence Notch target gene selection and activity. However, the mechanism b...

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Détails bibliographiques
Auteurs principaux: Weaver, Kelly L., Alves-Guerra, Marie-Clotilde, Jin, Ke, Wang, Zhiqiang, Han, Xiaoqing, Ranganathan, Prathibha, Zhu, Xiaoxia, DaSilva, Thiago, Liu, Wei, Ratti, Francesca, Demarest, Renee M., Tzimas, Cristos, Rice, Meghan, Vasquez-Del Carpio, Rodrigo, Dahmane, Nadia, Robbins, David J., Capobianco, Anthony J.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154994/
https://ncbi.nlm.nih.gov/pubmed/25038227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1547
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