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Assembly of a Notch Transcriptional Activation Complex Requires Multimerization

Notch transmembrane receptors direct essential cellular processes, such as proliferation and differentiation, through direct cell-to-cell interactions. Inappropriate release of the intracellular domain of Notch (N(ICD)) from the plasma membrane results in the accumulation of deregulated nuclear N(IC...

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Detalhes bibliográficos
Main Authors: Vasquez-Del Carpio, Rodrigo, Kaplan, Fred M., Weaver, Kelly L., VanWye, Jeffrey D., Alves-Guerra, Marie-Clotilde, Robbins, David J., Capobianco, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135300/
https://ncbi.nlm.nih.gov/pubmed/21245387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00360-10
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