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Neoplastic Transformation by Notch Requires Nuclear Localization

Notch proteins are plasma membrane-spanning receptors that mediate important cell fate decisions such as differentiation, proliferation, and apoptosis. The mechanism of Notch signaling remains poorly understood. However, it is clear that the Notch signaling pathway mediates its effects through inter...

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Detalhes bibliográficos
Main Authors: Jeffries, Shawn, Capobianco, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85741/
https://ncbi.nlm.nih.gov/pubmed/10805736
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