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Induction of Cyclin D1 Transcription and CDK2 Activity by Notch(ic): Implication for Cell Cycle Disruption in Transformation by Notch(ic)
Notch genes encode a family of transmembrane proteins that are involved in many cellular processes such as differentiation, proliferation, and apoptosis. Although it is well established that all four Notch genes can act as oncogenes, the mechanism by which Notch proteins transform cells remains unkn...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87311/ https://ncbi.nlm.nih.gov/pubmed/11486031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5925-5934.2001 |
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