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Neoplastic Transformation by Notch Requires Nuclear Localization

Notch proteins are plasma membrane-spanning receptors that mediate important cell fate decisions such as differentiation, proliferation, and apoptosis. The mechanism of Notch signaling remains poorly understood. However, it is clear that the Notch signaling pathway mediates its effects through inter...

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Hlavní autoři: Jeffries, Shawn, Capobianco, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85741/
https://ncbi.nlm.nih.gov/pubmed/10805736
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