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Neoplastic Transformation by Notch Requires Nuclear Localization

Notch proteins are plasma membrane-spanning receptors that mediate important cell fate decisions such as differentiation, proliferation, and apoptosis. The mechanism of Notch signaling remains poorly understood. However, it is clear that the Notch signaling pathway mediates its effects through inter...

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Bibliografiske detaljer
Main Authors: Jeffries, Shawn, Capobianco, Anthony J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85741/
https://ncbi.nlm.nih.gov/pubmed/10805736
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