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Neoplastic Transformation by Notch Requires Nuclear Localization

Notch proteins are plasma membrane-spanning receptors that mediate important cell fate decisions such as differentiation, proliferation, and apoptosis. The mechanism of Notch signaling remains poorly understood. However, it is clear that the Notch signaling pathway mediates its effects through inter...

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Main Authors: Jeffries, Shawn, Capobianco, Anthony J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC85741/
https://ncbi.nlm.nih.gov/pubmed/10805736
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