Hierarchical Phosphorylation within the Ankyrin Repeat Domain Defines a Phosphoregulatory Loop That Regulates Notch Transcriptional Activity

The Notch signal transduction pathway mediates important cellular functions through direct cell-to-cell contact. Deregulation of Notch activity can lead to an altered cell proliferation and has been linked to many human cancers. Casein kinase 2 (CK2), a ubiquitous kinase, regulates several cellular...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ranganathan, Prathibha, Vasquez-Del Carpio, Rodrigo, Kaplan, Fred M., Wang, Hong, Gupta, Ashu, VanWye, Jeffrey D., Capobianco, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190692/
https://ncbi.nlm.nih.gov/pubmed/21685388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243600
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados