Notch Signaling Drives Stemness and Tumorigenicity of Esophageal Adenocarcinoma

Esophageal adenocarcinoma (EAC) ranks sixth in cancer mortality in the world and its incidence has risen dramatically in the western population over the last decades. Data presented herein strongly suggest that Notch signaling is critical for EAC and underlies resistance to chemotherapy. We present...

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Pubblicato in:Cancer Res
Autori principali: Wang, Zhiqiang, Da Silva, Thiago G., Jin, Ke, Han, Xiaoqin, Ranganathan, Prathibha, Zhu, Xiaoxia, Sanchez-Mejias, Avencia, Bai, Feng, Li, Bin, Fei, Dennis Liang, Weaver, Kelly, Carpio, Rodrigo Vasquez-Del, Moscowitz, Anna E., Koshenkov, Vadim P., Sanchez, Lilly, Sparling, Lynne, Pei, Xin-Hai, Franceschi, Dido, Ribeiro, Afonso, Robbins, David J., Livingstone, Alan S., Capobianco, Anthony J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527315/
https://ncbi.nlm.nih.gov/pubmed/25164006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2051
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