Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex

It is well established that Notch functions as a transcriptional activator through the formation of a ternary complex that comprises Notch, Maml and CSL. This ternary complex then serves to recruit additional transcriptional cofactors that link to higher order transcriptional complexes. The mechanis...

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Bibliographic Details
Published in:Mol Cancer Res
Main Authors: Han, Xiaoqing, Ranganathan, Prathibha, Tzimas, Christos, Weaver, Kelly L., Jin, Ke, Astudillo, Luisana, Zhou, Wen, Zhu, Xiaoxia, Li, Bin, Robbins, David J., Capobianco, Anthony J.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581691/
https://ncbi.nlm.nih.gov/pubmed/28584023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0241
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