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Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation

Histone H2A monoubiquitylation (H2Aub) is considered to be a key effector in transcriptional repression by Polycomb-repressive complex 1 (PRC1). We analyzed Drosophila with a point mutation in the PRC1 subunit Sce that abolishes its H2A ubiquitylase activity or with point mutations in the H2A and H2...

詳細記述

保存先:
書誌詳細
出版年:Genes Dev
主要な著者: Pengelly, Ana Raquel, Kalb, Reinhard, Finkl, Katja, Müller, Jürg
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526733/
https://ncbi.nlm.nih.gov/pubmed/26178786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.265439.115
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