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PRC2 is dispensable for HOTAIR‐mediated transcriptional repression

Long non‐coding RNAs (lncRNAs) play diverse roles in physiological and pathological processes. Several lncRNAs have been suggested to modulate gene expression by guiding chromatin‐modifying complexes to specific sites in the genome. However, besides the example of Xist, clear‐cut evidence demonstrat...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Portoso, Manuela, Ragazzini, Roberta, Brenčič, Živa, Moiani, Arianna, Michaud, Audrey, Vassilev, Ivaylo, Wassef, Michel, Servant, Nicolas, Sargueil, Bruno, Margueron, Raphaël
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391141/
https://ncbi.nlm.nih.gov/pubmed/28167697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695335
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