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Targeting the IRE1α-XBP1 Branch of the Unfolded Protein Response in Human Diseases
Accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) leads to ER stress, which is characteristic of cells with high level of secretory activity and implicated in a variety of disease conditions. In response to ER stress, the cell elicits an adaptive process called the Unf...
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| Publicat a: | Semin Cancer Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523453/ https://ncbi.nlm.nih.gov/pubmed/25986851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.04.010 |
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