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The IRE1α-XBP1 Pathway of the Unfolded Protein Response is Required for Adipogenesis
Signaling cascades during adipogenesis culminate in the expression of two essential adipogenic factors, PPARγ and C/EBPα . Here we demonstrate that the IRE1α-XBP1 pathway, the most conserved branch of the unfolded protein response (UPR), is indispensable for adipogenesis. Indeed, XBP1-deficient mous...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963107/ https://ncbi.nlm.nih.gov/pubmed/19490910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.04.009 |
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