The IRE1α-XBP1 Pathway of the Unfolded Protein Response is Required for Adipogenesis

Signaling cascades during adipogenesis culminate in the expression of two essential adipogenic factors, PPARγ and C/EBPα . Here we demonstrate that the IRE1α-XBP1 pathway, the most conserved branch of the unfolded protein response (UPR), is indispensable for adipogenesis. Indeed, XBP1-deficient mous...

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Bibliografische gegevens
Hoofdauteurs: Sha, Haibo, He, Yin, Chen, Hui, Wang, Cindy, Zenno, Anna, Shi, Hang, Yang, Xiaoyong, Zhang, Xinmin, Qi, Ling
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963107/
https://ncbi.nlm.nih.gov/pubmed/19490910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.04.009
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