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Targeting the IRE1α-XBP1 Branch of the Unfolded Protein Response in Human Diseases
Accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) leads to ER stress, which is characteristic of cells with high level of secretory activity and implicated in a variety of disease conditions. In response to ER stress, the cell elicits an adaptive process called the Unf...
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| Publicado no: | Semin Cancer Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523453/ https://ncbi.nlm.nih.gov/pubmed/25986851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2015.04.010 |
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