IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis

The unfolded protein response (UPR) is a cellular adaptive mechanism that is activated in response to the accumulation of unfolded proteins in the endoplasmic reticulum. The inositol-requiring protein-1α/X-box–binding protein–mediated (IRE1α/XBP1-mediated) branch of the UPR is highly conserved and h...

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Udgivet i:J Clin Invest
Main Authors: Tohmonda, Takahide, Yoda, Masaki, Iwawaki, Takao, Matsumoto, Morio, Nakamura, Masaya, Mikoshiba, Katsuhiko, Toyama, Yoshiaki, Horiuchi, Keisuke
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563737/
https://ncbi.nlm.nih.gov/pubmed/26193638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76765
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