載入...
The novel β2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells
PURPOSE: Proteasome-inhibiting drugs (PI) are gaining importance in hematologic oncology. The proteasome carries three proteolytically active subunits (β1, β2, β5). All established PI (bortezomib and carfilzomib), as well as experimental drugs in the field (dalanzomib, oprozomib, and ixazomib), by d...
Na minha lista:
| 發表在: | Cancer Chemother Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer Berlin Heidelberg
2015
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4515249/ https://ncbi.nlm.nih.gov/pubmed/26099967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2801-0 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|