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An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors
Proteasome inhibitors bortezomib, carfilzomib and ixazomib (approved by the US Food and Drug Administration [FDA]) induce remissions in patients with multiple myeloma (MM), but most patients eventually become resistant. MM and other hematologic malignancies express ubiquitous constitutive proteasome...
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| Опубликовано в: : | Blood Adv |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177641/ https://ncbi.nlm.nih.gov/pubmed/30266819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018016360 |
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