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Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome’s Chymotrypsin-like Sites
Proteasomal processing is conducted by three individual catalytic subunits, namely β1, β2, and β5. Subunit-specific inhibitors are useful tools in dissecting the role of these individual subunits and are leads toward the development of antitumor agents. We here report that the presence of fluorinate...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037272/ https://ncbi.nlm.nih.gov/pubmed/20131905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9015685 |
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