The potential of CRISPR/Cas9 genome editing for the study and treatment of intervertebral disc pathologies

by Krupkova, Olga, Cambria, Elena, Besse, Lenka, Besse, Andrej, Bowles, Robert, Wuertz‐Kozak, Karin
Published in JOR Spine (2018)

Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells

by Byrgazov, Konstantin, Besse, Andrej, Kraus, Marianne, Slipicevic, Ana, Lehmann, Fredrik, Driessen, Christoph, Besse, Lenka
Published in Hemasphere (2021)

MicroRNAs in urine are not biomarkers of multiple myeloma

by Sedlaříková, Lenka, Bešše, Lenka, Novosadová, Soňa, Kubaczková, Veronika, Radová, Lenka, Staník, Michal, Krejčí, Marta, Hájek, Roman, Ševčíková, Sabina
Published in J Negat Results Biomed (2015)

The novel β2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myel...

by Kraus, Johannes, Kraus, Marianne, Liu, Nora, Besse, Lenka, Bader, Jürgen, Geurink, Paul P., de Bruin, Gerjan, Kisselev, Alexei F., Overkleeft, Herman, Driessen, Christoph
Published in Cancer Chemother Pharmacol (2015)

Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma

by Besse, Lenka, Sedlarikova, Lenka, Kryukov, Fedor, Nekvindova, Jana, Radova, Lenka, Slaby, Ondrej, Kuglik, Petr, Almasi, Martina, Penka, Miroslav, Krejci, Marta, Adam, Zdenek, Pour, Ludek, Sevcikova, Sabina, Hajek, Roman
Published in PLoS One (2015)

A metabolic switch in proteasome inhibitor-resistant multiple myeloma ensures higher mitochondrial metabolism, protein folding and sphingomyelin synthesis

by Besse, Lenka, Besse, Andrej, Mendez-Lopez, Max, Vasickova, Katerina, Sedlackova, Miroslava, Vanhara, Petr, Kraus, Marianne, Bader, Jürgen, Ferreira, Renan B., Castellano, Ronald K., Law, Brian K., Driessen, Christoph
Published in Haematologica (2019)

Dynamics of tumor‐specific cfDNA in response to therapy in multiple myeloma patients

by Vrabel, David, Sedlarikova, Lenka, Besse, Lenka, Rihova, Lucie, Bezdekova, Renata, Almasi, Martina, Kubaczkova, Veronika, Brožová, Lucie, Jarkovsky, Jiri, Plonkova, Hana, Jelinek, Tomas, Sandecka, Viera, Stork, Martin, Pour, Ludek, Sevcikova, Sabina, Hajek, Roman
Published in Eur J Haematol (2019)

Promising activity of nelfinavir-bortezomib-dexamethasone in proteasome inhibitor–refractory multiple myeloma

by Driessen, Christoph, Müller, Rouven, Novak, Urban, Cantoni, Nathan, Betticher, Daniel, Mach, Nicolas, Rüfer, Axel, Mey, Ulrich, Samaras, Panagiotis, Ribi, Karin, Besse, Lenka, Besse, Andrej, Berset, Catherine, Rondeau, Stephanie, Hawle, Hanne, Hitz, Felicitas, Pabst, Thomas, Zander, Thilo
Published in Blood (2018)

Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis

by Brenig, Robert, Pop, Oltin T, Triantafyllou, Evangelos, Geng, Anne, Singanayagam, Arjuna, Perez-Shibayama, Christian, Besse, Lenka, Cupovic, Jovana, Künzler, Patrizia, Boldanova, Tuyana, Brand, Stephan, Semela, David, Duong, François HT, Weston, Christopher J, Ludewig, Burkhard, Heim, Markus H, Wendon, Julia, Antoniades, Charalambos G, Bernsmeier, Christine
Published in Life Sci Alliance (2019)

Treatment with HIV-Protease Inhibitor Nelfinavir Identifies Membrane Lipid Composition and Fluidity as a Therapeutic Target in Advanced Multiple Myeloma

by Besse, Lenka, Besse, Andrej, Stolze, Sara C., Sobh, Amin, Zaal, Esther A., van der Ham, Alwin J., Ruiz, Mario, Phuyal, Santosh, Büchler, Lorina, Sathianathan, Marc, Florea, Bogdan I., Borén, Jan, Ståhlman, Marcus, Huber, Julia, Bolomsky, Arnold, Ludwig, Heinz, Hannich, J. Thomas, Loguinov, Alex, Everts, Bart, Berkers, Celia R., Pilon, Marc, Farhan, Hesso, Vulpe, Christopher D., Overkleeft, Herman S., Driessen, Christoph
Published in Cancer Res (2021)