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The potential of CRISPR/Cas9 genome editing for the study and treatment of intervertebral disc pathologies

The CRISPR/Cas9 system has emerged as a powerful tool for mammalian genome engineering. In basic and translational intervertebral disc (IVD) research, this technique has remarkable potential to answer fundamental questions on pathway interactions, to simulate IVD pathologies, and to promote drug dev...

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Bibliografiske detaljer
Udgivet i:JOR Spine
Main Authors: Krupkova, Olga, Cambria, Elena, Besse, Lenka, Besse, Andrej, Bowles, Robert, Wuertz‐Kozak, Karin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686831/
https://ncbi.nlm.nih.gov/pubmed/31463435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1003
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