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Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations
Cancer immunotherapy has shown impressive results, but most patients do not respond. We hypothesized that the effector response in the tumour could be visualized as a complex network of interacting gene products and that by mapping this network we could predict effective pharmacological intervention...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4508665/ https://ncbi.nlm.nih.gov/pubmed/26193793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12298 |
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