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Synergistic Effect of CTLA-4 Blockade and Cancer Chemotherapy in the Induction of Anti-Tumor Immunity

Several chemotherapeutics exert immunomodulatory effects. One of these is the nucleoside analogue gemcitabine, which is widely used in patients with lung cancer, ovarian cancer, breast cancer, mesothelioma and several other types of cancer, but with limited efficacy. We hypothesized that the immunop...

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Detalhes bibliográficos
Main Authors: Lesterhuis, W. Joost, Salmons, Joanne, Nowak, Anna K., Rozali, Esdy N., Khong, Andrea, Dick, Ian M., Harken, Julie A., Robinson, Bruce W., Lake, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633941/
https://ncbi.nlm.nih.gov/pubmed/23626745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061895
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