Programmed Death Ligand 2 in Cancer-Induced Immune Suppression

Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. The relevance of the PD-1/PD-L1 pathw...

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Bibliographic Details
Main Authors: Rozali, Esdy N., Hato, Stanleyson V., Robinson, Bruce W., Lake, Richard A., Lesterhuis, W. Joost
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350956/
https://ncbi.nlm.nih.gov/pubmed/22611421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/656340
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