Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment

Dexamethasone is a synthetic glucocorticoid commonly used for the prevention and management of side effects in cancer patients undergoing chemotherapy. While it is effective as an anti-emetic and in preventing hypersensitivity reactions, dexamethasone depletes peripheral blood lymphocytes and impact...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Aston, Wayne J., Hope, Danika E., Cook, Alistair M., Boon, Louis, Dick, Ian, Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791454/
https://ncbi.nlm.nih.gov/pubmed/31646089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1641390
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