Transient Treg depletion enhances therapeutic anti‐cancer vaccination

INTRODUCTION: Regulatory T cells (Treg) play an important role in suppressing anti‐ immunity and their depletion has been linked to improved outcomes. To better understand the role of Treg in limiting the efficacy of anti‐cancer immunity, we used a Diphtheria toxin (DTX) transgenic mouse model to sp...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Fisher, Scott A., Aston, Wayne J., Chee, Jonathan, Khong, Andrea, Cleaver, Amanda L., Solin, Jessica N., Ma, Shaokang, Lesterhuis, W. Joost, Dick, Ian, Holt, Robert A., Creaney, Jenette, Boon, Louis, Robinson, Bruce, Lake, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322183/
https://ncbi.nlm.nih.gov/pubmed/28250921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.136
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