Transient Treg depletion enhances therapeutic anti‐cancer vaccination

INTRODUCTION: Regulatory T cells (Treg) play an important role in suppressing anti‐ immunity and their depletion has been linked to improved outcomes. To better understand the role of Treg in limiting the efficacy of anti‐cancer immunity, we used a Diphtheria toxin (DTX) transgenic mouse model to sp...

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Bibliografiska uppgifter
I publikationen:Immun Inflamm Dis
Huvudupphovsmän: Fisher, Scott A., Aston, Wayne J., Chee, Jonathan, Khong, Andrea, Cleaver, Amanda L., Solin, Jessica N., Ma, Shaokang, Lesterhuis, W. Joost, Dick, Ian, Holt, Robert A., Creaney, Jenette, Boon, Louis, Robinson, Bruce, Lake, Richard A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322183/
https://ncbi.nlm.nih.gov/pubmed/28250921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.136
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