Transient Treg depletion enhances therapeutic anti‐cancer vaccination

INTRODUCTION: Regulatory T cells (Treg) play an important role in suppressing anti‐ immunity and their depletion has been linked to improved outcomes. To better understand the role of Treg in limiting the efficacy of anti‐cancer immunity, we used a Diphtheria toxin (DTX) transgenic mouse model to sp...

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Detalles Bibliográficos
Publicado en:Immun Inflamm Dis
Autores principales: Fisher, Scott A., Aston, Wayne J., Chee, Jonathan, Khong, Andrea, Cleaver, Amanda L., Solin, Jessica N., Ma, Shaokang, Lesterhuis, W. Joost, Dick, Ian, Holt, Robert A., Creaney, Jenette, Boon, Louis, Robinson, Bruce, Lake, Richard A.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322183/
https://ncbi.nlm.nih.gov/pubmed/28250921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.136
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