Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

Immune checkpoint blockade (ICPB) is a powerfully effective cancer therapy in some patients. Tumor neo-antigens are likely main targets for attack but it is not clear which and how many tumor mutations in individual cancers are actually antigenic, with or without ICPB therapy and their role as neo-a...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Ma, Shaokang, Chee, Jonathan, Fear, Vanessa S., Forbes, Catherine A., Boon, Louis, Dick, Ian M., Robinson, Bruce W. S., Creaney, Jenette
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959436/
https://ncbi.nlm.nih.gov/pubmed/32002299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1684714
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