Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

Immune checkpoint blockade (ICPB) is a powerfully effective cancer therapy in some patients. Tumor neo-antigens are likely main targets for attack but it is not clear which and how many tumor mutations in individual cancers are actually antigenic, with or without ICPB therapy and their role as neo-a...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Ma, Shaokang, Chee, Jonathan, Fear, Vanessa S., Forbes, Catherine A., Boon, Louis, Dick, Ian M., Robinson, Bruce W. S., Creaney, Jenette
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959436/
https://ncbi.nlm.nih.gov/pubmed/32002299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1684714
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