טוען...
Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy
PD-1/PD-L1 checkpoint therapy for cancer is commonly considered to act by reactivating T cells in the tumor microenvironment. Here, we present data from 2 mouse tumor models demonstrating an essential involvement of tumor-draining lymph nodes in PD-1 and PD-L1 therapeutic efficacy. Immune activation...
שמור ב:
| הוצא לאור ב: | JCI Insight |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6328025/ https://ncbi.nlm.nih.gov/pubmed/30518694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124507 |
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