Pre-treatment tumor neo-antigen responses in draining lymph nodes are infrequent but predict checkpoint blockade therapy outcome

Immune checkpoint blockade (ICPB) is a powerfully effective cancer therapy in some patients. Tumor neo-antigens are likely main targets for attack but it is not clear which and how many tumor mutations in individual cancers are actually antigenic, with or without ICPB therapy and their role as neo-a...

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Vydáno v:Oncoimmunology
Hlavní autoři: Ma, Shaokang, Chee, Jonathan, Fear, Vanessa S., Forbes, Catherine A., Boon, Louis, Dick, Ian M., Robinson, Bruce W. S., Creaney, Jenette
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959436/
https://ncbi.nlm.nih.gov/pubmed/32002299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1684714
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