Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response

IMPORTANCE: Understanding molecular mechanisms of response and resistance to anticancer therapies requires prospective patient follow-up and clinical and functional validation of both common and low-frequency mutations. We describe a whole-exome sequencing (WES) precision medicine trial focused on p...

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Xehetasun bibliografikoak
Argitaratua izan da:JAMA Oncol
Egile Nagusiak: Beltran, Himisha, Eng, Kenneth, Mosquera, Juan Miguel, Sigaras, Alexandros, Romanel, Alessandro, Rennert, Hanna, Kossai, Myriam, Pauli, Chantal, Faltas, Bishoy, Fontugne, Jacqueline, Park, Kyung, Banfelder, Jason, Prandi, Davide, Madhukar, Neel, Zhang, Tuo, Padilla, Jessica, Greco, Noah, McNary, Terra J., Herrscher, Erick, Wilkes, David, MacDonald, Theresa Y., Xue, Hui, Vacic, Vladimir, Emde, Anne-Katrin, Oschwald, Dayna, Tan, Adrian Y., Chen, Zhengming, Collins, Colin, Gleave, Martin E., Wang, Yuzhuo, Chakravarty, Dimple, Schiffman, Marc, Kim, Robert, Campagne, Fabien, Robinson, Brian D., Nanus, David M., Tagawa, Scott T., Xiang, Jenny Z., Smogorzewska, Agata, Demichelis, Francesca, Rickman, David S., Sboner, Andrea, Elemento, Olivier, Rubin, Mark A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505739/
https://ncbi.nlm.nih.gov/pubmed/26181256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.1313
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