Clonal Evolution of Chemotherapy-resistant Urothelial Carcinoma

Chemotherapy-resistant urothelial carcinoma (UC) has no uniformly curative therapy. Understanding how selective pressure from chemotherapy directs UC’s evolution and shapes its clonal architecture is a central biological question with clinical implications. To address this question, we performed who...

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Publicado en:Nat Genet
Main Authors: Faltas, Bishoy M., Prandi, Davide, Tagawa, Scott T., Molina, Ana M., Nanus, David M., Sternberg, Cora, Rosenberg, Jonathan, Mosquera, Juan Miguel, Robinson, Brian, Elemento, Olivier, Sboner, Andrea, Beltran, Himisha, Demichelis, Francesca, Rubin, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549141/
https://ncbi.nlm.nih.gov/pubmed/27749842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3692
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