Common germline-somatic variant interactions in advanced urothelial cancer

The prevalence and biological consequences of deleterious germline variants in urothelial cancer (UC) are not fully characterized. We performed whole-exome sequencing (WES) of germline DNA and 157 primary and metastatic tumors from 80 UC patients. We developed a computational framework for identifyi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Vosoughi, Aram, Zhang, Tuo, Shohdy, Kyrillus S., Vlachostergios, Panagiotis J., Wilkes, David C., Bhinder, Bhavneet, Tagawa, Scott T., Nanus, David M., Molina, Ana M., Beltran, Himisha, Sternberg, Cora N., Motanagh, Samaneh, Robinson, Brian D., Xiang, Jenny, Fan, Xiao, Chung, Wendy K., Rubin, Mark A., Elemento, Olivier, Sboner, Andrea, Mosquera, Juan Miguel, Faltas, Bishoy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713129/
https://ncbi.nlm.nih.gov/pubmed/33273457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19971-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky