Unraveling the clonal hierarchy of somatic genomic aberrations

Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of tumor admixture and ploidy infers the clonal hierarchy of genomic aberrations. Comparative...

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Autors principals: Prandi, Davide, Baca, Sylvan C, Romanel, Alessandro, Barbieri, Christopher E, Mosquera, Juan-Miguel, Fontugne, Jacqueline, Beltran, Himisha, Sboner, Andrea, Garraway, Levi A, Rubin, Mark A, Demichelis, Francesca
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167267/
https://ncbi.nlm.nih.gov/pubmed/25160065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0439-6
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