Unraveling the clonal hierarchy of somatic genomic aberrations

Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of tumor admixture and ploidy infers the clonal hierarchy of genomic aberrations. Comparative...

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Hauptverfasser: Prandi, Davide, Baca, Sylvan C, Romanel, Alessandro, Barbieri, Christopher E, Mosquera, Juan-Miguel, Fontugne, Jacqueline, Beltran, Himisha, Sboner, Andrea, Garraway, Levi A, Rubin, Mark A, Demichelis, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167267/
https://ncbi.nlm.nih.gov/pubmed/25160065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0439-6
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