Unraveling the clonal hierarchy of somatic genomic aberrations

Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of tumor admixture and ploidy infers the clonal hierarchy of genomic aberrations. Comparative...

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Detalles Bibliográficos
Autores principales: Prandi, Davide, Baca, Sylvan C, Romanel, Alessandro, Barbieri, Christopher E, Mosquera, Juan-Miguel, Fontugne, Jacqueline, Beltran, Himisha, Sboner, Andrea, Garraway, Levi A, Rubin, Mark A, Demichelis, Francesca
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167267/
https://ncbi.nlm.nih.gov/pubmed/25160065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0439-6
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