Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response

IMPORTANCE: Understanding molecular mechanisms of response and resistance to anticancer therapies requires prospective patient follow-up and clinical and functional validation of both common and low-frequency mutations. We describe a whole-exome sequencing (WES) precision medicine trial focused on p...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JAMA Oncol
Prif Awduron: Beltran, Himisha, Eng, Kenneth, Mosquera, Juan Miguel, Sigaras, Alexandros, Romanel, Alessandro, Rennert, Hanna, Kossai, Myriam, Pauli, Chantal, Faltas, Bishoy, Fontugne, Jacqueline, Park, Kyung, Banfelder, Jason, Prandi, Davide, Madhukar, Neel, Zhang, Tuo, Padilla, Jessica, Greco, Noah, McNary, Terra J., Herrscher, Erick, Wilkes, David, MacDonald, Theresa Y., Xue, Hui, Vacic, Vladimir, Emde, Anne-Katrin, Oschwald, Dayna, Tan, Adrian Y., Chen, Zhengming, Collins, Colin, Gleave, Martin E., Wang, Yuzhuo, Chakravarty, Dimple, Schiffman, Marc, Kim, Robert, Campagne, Fabien, Robinson, Brian D., Nanus, David M., Tagawa, Scott T., Xiang, Jenny Z., Smogorzewska, Agata, Demichelis, Francesca, Rickman, David S., Sboner, Andrea, Elemento, Olivier, Rubin, Mark A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505739/
https://ncbi.nlm.nih.gov/pubmed/26181256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.1313
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