Pharmacologic inhibition of the NLRP3 inflammasome preserves cardiac function after ischemic and non-ischemic injury in the mouse

BACKGROUND: Sterile inflammation resulting from myocardial injury activates the NLRP3 inflammasome and amplifies the inflammatory response mediating further damage. METHODS: We used two experimental models of ischemic injury (acute myocardial infarction [AMI] with and without reperfusion) and a mode...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Cardiovasc Pharmacol
Autors principals: Marchetti, Carlo, Toldo, Stefano, Chojnacki, Jeremy, Mezzaroma, Eleonora, Liu, Kai, Salloum, Fadi N., Nordio, Andrea, Carbone, Salvatore, Mauro, Adolfo Gabriele, Das, Anindita, Zalavadia, Ankit A., Halquist, Matthew S., Federici, Massimo, Van Tassell, Benjamin W., Zhang, Shijun, Abbate, Antonio
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500673/
https://ncbi.nlm.nih.gov/pubmed/25915511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000247
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars