Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation

Mammalian cells contain copious amounts of RNA including both coding and noncoding RNA (ncRNA). Generally the ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Among ncRNA, the long ncRNA and small ncRNA can affect histone modification, DNA methylatio...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Zhang, Guoqiang, Estève, Pierre-Olivier, Chin, Hang Gyeong, Terragni, Jolyon, Dai, Nan, Corrêa, Ivan R., Pradhan, Sriharsa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Nucleic Acid Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499142/
https://ncbi.nlm.nih.gov/pubmed/25990724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv518
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