Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation

Mammalian cells contain copious amounts of RNA including both coding and noncoding RNA (ncRNA). Generally the ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Among ncRNA, the long ncRNA and small ncRNA can affect histone modification, DNA methylatio...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Zhang, Guoqiang, Estève, Pierre-Olivier, Chin, Hang Gyeong, Terragni, Jolyon, Dai, Nan, Corrêa, Ivan R., Pradhan, Sriharsa
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499142/
https://ncbi.nlm.nih.gov/pubmed/25990724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv518
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