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Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters
DNA (cytosine-5)-methyltransferase (DNMT) 1 participates in transcriptional repression of genes by methylation-dependent and -independent mechanisms. Here, DNMT1 is shown to bind p53 and colocalize in the nucleus. DNMT1-mediated methylation is stimulated by p53 in vitro. Upon p53 induction, a report...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2005
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544618/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15657147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407729102 |
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